Item Type | Name |
Concept
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Double-Blind Method
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Academic Article
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Efficacy and safety of a new HMG-CoA reductase inhibitor, atorvastatin, in patients with hypertriglyceridemia.
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Academic Article
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A psyllium-enriched cereal for the treatment of hypercholesterolemia in children: a controlled, double-blind, crossover study.
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Academic Article
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Efficacy and safety of lovastatin in adolescent males with heterozygous familial hypercholesterolemia: a randomized controlled trial.
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Academic Article
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Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: a randomized controlled trial.
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Academic Article
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The lipid-lowering effects of atorvastatin, a new HMG-CoA reductase inhibitor: results of a randomized, double-masked study.
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Academic Article
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Lipid-altering efficacy and safety of simvastatin 80 mg/day: long-term experience in a large group of patients with hypercholesterolemia. World Wide Expanded Dose Simvastatin Study Group.
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Academic Article
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Colesevelam hydrochloride (cholestagel): a new, potent bile acid sequestrant associated with a low incidence of gastrointestinal side effects.
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Academic Article
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Comparison of one-year efficacy and safety of atorvastatin versus lovastatin in primary hypercholesterolemia. Atorvastatin Study Group I.
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Academic Article
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Safety and pharmacokinetic study with escalating doses of 3-acetyl-7-oxo-dehydroepiandrosterone in healthy male volunteers.
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Academic Article
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Efficacy and short-term safety of a new ACAT inhibitor, avasimibe, on lipids, lipoproteins, and apolipoproteins, in patients with combined hyperlipidemia.
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Academic Article
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A comparison of simvastatin and atorvastatin up to maximal recommended doses in a large multicenter randomized clinical trial.
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Academic Article
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Long-term effects of consuming foods containing psyllium seed husk on serum lipids in subjects with hypercholesterolemia.
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Academic Article
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Effects of continuous estrogen and estrogen-progestin replacement regimens on cardiovascular risk markers in postmenopausal women.
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Academic Article
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Effect of m-chlorophenylpiperazine on plasma homovanillic acid concentrations in healthy subjects.
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Academic Article
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Effect of the novel antiplatelet agent cilostazol on plasma lipoproteins in patients with intermittent claudication.
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Academic Article
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Reduction of LDL cholesterol in patients with primary hypercholesterolemia by SCH 48461: results of a multicenter dose-ranging study.
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Academic Article
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Rapid onset of therapeutic effect of risperidone versus haloperidol in a double-blind randomized trial.
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Academic Article
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Lipid responses to plant-sterol-enriched reduced-fat spreads incorporated into a National Cholesterol Education Program Step I diet.
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Academic Article
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Cholesterol lowering with high-viscosity hydroxypropylmethylcellulose.
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Academic Article
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Effects of simvastatin (40 and 80 mg/day) in patients with mixed hyperlipidemia.
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Academic Article
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Effects of high-dose simvastatin on adrenal and gonadal steroidogenesis in men with hypercholesterolemia.
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Academic Article
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Lipid-altering efficacy and safety of simvastatin 80 mg/day: worldwide long-term experience in patients with hypercholesterolemia.
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Academic Article
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Significant differential effects of alendronate, estrogen, or combination therapy on the rate of bone loss after discontinuation of treatment of postmenopausal osteoporosis. A randomized, double-blind, placebo-controlled trial.
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Academic Article
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Comparison of the efficacy of atorvastatin versus cerivastatin in primary hypercholesterolemia.
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Academic Article
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Effectiveness of colesevelam hydrochloride in decreasing LDL cholesterol in patients with primary hypercholesterolemia: a 24-week randomized controlled trial.
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Academic Article
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Comparison of effects of simvastatin versus atorvastatin on high-density lipoprotein cholesterol and apolipoprotein A-I levels.
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Academic Article
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Safety and tolerability of esterified phytosterols administered in reduced-fat spread and salad dressing to healthy adult men and women.
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Academic Article
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Lipid and apolipoprotein ratios: association with coronary artery disease and effects of rosuvastatin compared with atorvastatin, pravastatin, and simvastatin.
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Academic Article
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Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia.
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Academic Article
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Effects of simvastatin, an HMG-CoA reductase inhibitor, in patients with hypertriglyceridemia.
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Academic Article
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The safety and immunogenicity of a CETP vaccine in healthy adults.
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Academic Article
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Lipid responses in mildly hypertriglyceridemic men and women to consumption of docosahexaenoic acid-enriched eggs.
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Academic Article
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A multicenter, randomized, double-blind clinical trial comparing the low-density lipoprotein cholesterol-lowering ability of lovastatin 10, 20, and 40 mg/d with fluvastatin 20 and 40 mg/d.
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Academic Article
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Consumption of diacylglycerol oil as part of a reduced-energy diet enhances loss of body weight and fat in comparison with consumption of a triacylglycerol control oil.
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Academic Article
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Comparison of effects on low-density lipoprotein cholesterol and high-density lipoprotein cholesterol with rosuvastatin versus atorvastatin in patients with type IIa or IIb hypercholesterolemia.
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Academic Article
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Galantamine provides sustained benefits in patients with 'advanced moderate' Alzheimer's disease for at least 12 months.
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Academic Article
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Food products containing free tall oil-based phytosterols and oat beta-glucan lower serum total and LDL cholesterol in hypercholesterolemic adults.
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Academic Article
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Aggressive versus moderate lipid-lowering therapy in hypercholesterolemic postmenopausal women: Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES).
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Academic Article
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Lipid responses to a dietary docosahexaenoic acid supplement in men and women with below average levels of high density lipoprotein cholesterol.
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Academic Article
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Efficacy and safety profile of fenofibrate-coated microgranules 130 mg, with and without food, in patients with hypertriglyceridemia and the metabolic syndrome: an 8-week, randomized, double-blind, placebo-controlled study.
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Academic Article
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Effects of colesevelam hydrochloride on low-density lipoprotein cholesterol and high-sensitivity C-reactive protein when added to statins in patients with hypercholesterolemia.
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Academic Article
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Effect of pioglitazone compared with glimepiride on carotid intima-media thickness in type 2 diabetes: a randomized trial.
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Academic Article
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Efficacy and safety of ezetimibe coadministered with statins: randomised, placebo-controlled, blinded experience in 2382 patients with primary hypercholesterolemia.
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Academic Article
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Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels on a background of atorvastatin.
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Academic Article
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Efficacy and tolerability of adding prescription omega-3 fatty acids 4 g/d to simvastatin 40 mg/d in hypertriglyceridemic patients: an 8-week, randomized, double-blind, placebo-controlled study.
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Academic Article
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The effect of darapladib on plasma lipoprotein-associated phospholipase A2 activity and cardiovascular biomarkers in patients with stable coronary heart disease or coronary heart disease risk equivalent: the results of a multicenter, randomized, double-blind, placebo-controlled study.
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Academic Article
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Flushing ASsessment Tool (FAST): psychometric properties of a new measure assessing flushing symptoms and clinical impact of niacin therapy.
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Academic Article
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Comparison of the safety and efficacy of a combination tablet of niacin extended release and simvastatin vs simvastatin monotherapy in patients with increased non-HDL cholesterol (from the SEACOAST I study).
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Academic Article
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ACAT inhibition and progression of carotid atherosclerosis in patients with familial hypercholesterolemia: the CAPTIVATE randomized trial.
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Academic Article
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Effects of consumption of pomegranate juice on carotid intima-media thickness in men and women at moderate risk for coronary heart disease.
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Academic Article
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Lipid-altering efficacy of the ezetimibe/simvastatin single tablet versus rosuvastatin in hypercholesterolemic patients.
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Academic Article
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Baseline lipoprotein lipids and low-density lipoprotein cholesterol response to prescription omega-3 acid ethyl ester added to Simvastatin therapy.
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Academic Article
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Efficacy and safety of torcetrapib, a novel cholesteryl ester transfer protein inhibitor, in individuals with below-average high-density lipoprotein cholesterol levels.
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Academic Article
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Low-density lipoprotein cholesterol reduction and goal achievement with ezetimibe/simvastatin versus atorvastatin or rosuvastatin in patients with diabetes, metabolic syndrome, or neither disease, stratified by National Cholesterol Education Program risk category.
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Academic Article
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Efficacy and safety of fenofibric acid co-administered with low- or moderate-dose statin in patients with mixed dyslipidemia and type 2 diabetes mellitus: results of a pooled subgroup analysis from three randomized, controlled, double-blind trials.
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Academic Article
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Effects of fenofibrate on atherogenic dyslipidemia in hypertriglyceridemic subjects.
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Academic Article
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Safety of anacetrapib in patients with or at high risk for coronary heart disease.
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Academic Article
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Flushing profile of extended-release niacin/laropiprant versus gradually titrated niacin extended-release in patients with dyslipidemia with and without ischemic cardiovascular disease.
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Academic Article
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One-year efficacy and safety of rosuvastatin + fenofibric acid combination therapy in patients with mixed dyslipidemia: evaluation of dose response.
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Academic Article
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Pioglitazone-mediated changes in lipoprotein particle composition are predicted by changes in adiponectin level in type 2 diabetes.
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Academic Article
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Evaluation of a new formulation of fenofibric acid, ABT-335, co-administered with statins : study design and rationale of a phase III clinical programme.
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Academic Article
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Effects of raloxifene and low-dose simvastatin coadministration on plasma lipids in postmenopausal women with primary hypercholesterolemia.
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Academic Article
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Design of the DEFINE trial: determining the EFficacy and tolerability of CETP INhibition with AnacEtrapib.
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Academic Article
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Peripheral artery disease, biomarkers, and darapladib.
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Academic Article
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Effect of CC chemokine receptor 2 CCR2 blockade on serum C-reactive protein in individuals at atherosclerotic risk and with a single nucleotide polymorphism of the monocyte chemoattractant protein-1 promoter region.
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Academic Article
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Reduction of LDL cholesterol by 25% to 60% in patients with primary hypercholesterolemia by atorvastatin, a new HMG-CoA reductase inhibitor.
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Academic Article
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Enhanced low-density lipoprotein cholesterol reduction and cost-effectiveness by low-dose colestipol plus lovastatin combination therapy.
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Academic Article
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Efficacy and tolerability of atorvastatin/fenofibrate fixed-dose combination tablet compared with atorvastatin and fenofibrate monotherapies in patients with dyslipidemia: a 12-week, multicenter, double-blind, randomized, parallel-group study.
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Academic Article
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Safety and efficacy of ezetimibe added on to rosuvastatin 5 or 10 mg versus up-titration of rosuvastatin in patients with hypercholesterolemia (the ACTE Study).
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Academic Article
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Bl-1020, a new ?-aminobutyric acid-enhanced antipsychotic: results of 6-week, randomized, double-blind, controlled, efficacy and safety study.
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Academic Article
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The efficacy and six-week tolerability of simvastatin 80 and 160 mg/day.
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Academic Article
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Effects of docosahexaenoic acid on serum lipoproteins in patients with combined hyperlipidemia: a randomized, double-blind, placebo-controlled trial.
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Academic Article
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A comparison of estrogen replacement, pravastatin, and combined treatment for the management of hypercholesterolemia in postmenopausal women.
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Academic Article
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Separate and joint effects of marine oil and simvastatin in patients with combined hyperlipidemia.
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Academic Article
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Efficacy and safety of simvastatin 80 mg/day in hypercholesterolemic patients. The Expanded Dose Simvastatin U.S. Study Group.
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Academic Article
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Effects of dietary inulin on serum lipids.
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Academic Article
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Long-term cholesterol-lowering effects of psyllium as an adjunct to diet therapy in the treatment of hypercholesterolemia.
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Academic Article
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Effect on high-density lipoprotein cholesterol of maximum dose simvastatin and atorvastatin in patients with hypercholesterolemia: results of the Comparative HDL Efficacy and Safety Study (CHESS).
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Academic Article
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Efficacy and safety of ABT-335 (fenofibric acid) in combination with rosuvastatin in patients with mixed dyslipidemia: a phase 3 study.
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Academic Article
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A 50-week extension study on the safety and efficacy of colesevelam in adults with primary hypercholesterolemia.
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Academic Article
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Predictors of anterior and posterior wall carotid intima media thickness progression in men and women at moderate risk of coronary heart disease.
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Academic Article
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Study design, rationale, and baseline characteristics: evaluation of fenofibric acid on carotid intima-media thickness in patients with type IIb dyslipidemia with residual risk in addition to atorvastatin therapy (FIRST) trial.
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Academic Article
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The effects of colestipol tablets compared with colestipol granules on plasma cholesterol and other lipids in moderately hypercholesterolemic patients.
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Academic Article
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Effect of combined risedronate and hormone replacement therapies on bone mineral density in postmenopausal women.
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Academic Article
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Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.
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Academic Article
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Efficacy and safety of an over-the-counter transdermal nicotine patch as an aid for smoking cessation.
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Academic Article
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The efficacy of magnetic resonance imaging in acute knee injuries.
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Academic Article
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Aggressive versus moderate lipid-lowering therapy in postmenopausal women with hypercholesterolemia: Rationale and design of the Beyond Endorsed Lipid Lowering with EBT Scanning (BELLES) trial.
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Academic Article
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Limitations of controlled augmentation trials in schizophrenia.
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Academic Article
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Over-the-counter nicotine patch therapy for smoking cessation: results from randomized, double-blind, placebo-controlled, and open label trials.
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Academic Article
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Premorbid functioning and treatment response in recent-onset schizophrenia.
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Academic Article
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Alendronate and estrogen effects in postmenopausal women with low bone mineral density. Alendronate/Estrogen Study Group.
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Academic Article
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Relationship between premorbid functioning and symptom severity as assessed at first episode of psychosis.
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Academic Article
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Postmenopausal uterine bleeding profiles with two forms of continuous combined hormone replacement therapy.
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Academic Article
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A multicenter, add-on randomized controlled trial of low-dose d-serine for negative and cognitive symptoms of schizophrenia.
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Academic Article
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A double-blind comparison of risperidone, quetiapine and placebo in patients with schizophrenia experiencing an acute exacerbation requiring hospitalization.
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Academic Article
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Lipid-altering efficacy and safety profile of co-administered extended release niacin/laropiprant and simvastatin versus atorvastatin in patients with mixed hyperlipidemia.
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Academic Article
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Marine oil capsule therapy for the treatment of hyperlipidemia.
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Academic Article
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Risperidone versus haloperidol in long-term hospitalized chronic patients in a double blind randomized trial: a post hoc analysis.
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Academic Article
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Treatment of cognitive impairment in early psychosis: a comparison of risperidone and haloperidol in a large long-term trial.
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Academic Article
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Cyclooxygenase-2 inhibition by rofecoxib reverses naturally occurring fever in humans.
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Academic Article
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Venous leg ulceration: evaluation of zinc treatment, serum zinc and rate of healing.
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Academic Article
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Efficacy and safety of a novel dual modulator of adenosine triphosphate-citrate lyase and adenosine monophosphate-activated protein kinase in patients with hypercholesterolemia: results of a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial.
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Academic Article
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Risperidone and haloperidol in first-episode psychosis: a long-term randomized trial.
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Academic Article
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Inhibition of intestinal cholesterol absorption with ezetimibe increases components of reverse cholesterol transport in humans.
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Academic Article
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Assessment of the effect of esterified propoxylated glycerol (EPG) on the status of fat-soluble vitamins and select water-soluble nutrients following dietary administration to humans for 8 weeks.
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Academic Article
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Effects of anacetrapib on plasma lipids in specific patient subgroups in the DEFINE (Determining the Efficacy and Tolerability of CETP INhibition with AnacEtrapib) trial.
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Academic Article
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Mipomersen, an apolipoprotein B synthesis inhibitor, reduces atherogenic lipoproteins in patients with severe hypercholesterolemia at high cardiovascular risk: a randomized, double-blind, placebo-controlled trial.
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Academic Article
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A highly bioavailable omega-3 free fatty acid formulation improves the cardiovascular risk profile in high-risk, statin-treated patients with residual hypertriglyceridemia (the ESPRIT trial).
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Academic Article
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Comparison of the lipid-lowering effects of pitavastatin 4 mg versus pravastatin 40 mg in adults with primary hyperlipidemia or mixed (combined) dyslipidemia: a Phase IV, prospective, US, multicenter, randomized, double-blind, superiority trial.
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Academic Article
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The efficacy of colesevelam HCl in the treatment of heterozygous familial hypercholesterolemia in pediatric and adult patients.
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Academic Article
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Effects of fenofibric acid on carotid intima-media thickness in patients with mixed dyslipidemia on atorvastatin therapy: randomized, placebo-controlled study (FIRST).
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Academic Article
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Olestra's effect on vitamins D and E in humans can be offset by increasing dietary levels of these vitamins.
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Academic Article
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Effects of omega-3 carboxylic acids on lipoprotein particles and other cardiovascular risk markers in high-risk statin-treated patients with residual hypertriglyceridemia: a randomized, controlled, double-blind trial.
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Academic Article
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Reductions in Atherogenic Lipids and Major Cardiovascular Events: A Pooled Analysis of 10 ODYSSEY Trials Comparing Alirocumab With Control.
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Academic Article
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The effect of omega-3 carboxylic acids on apolipoprotein CIII-containing lipoproteins in severe hypertriglyceridemia.
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Academic Article
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Effects of ipsapirone in healthy subjects: a dose-response study.
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Academic Article
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Omega-3 carboxylic acids in patients with severe hypertriglyceridemia: EVOLVE II, a randomized, placebo-controlled trial.
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Academic Article
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Cognitive Effects of MIN-101 in Patients With Schizophrenia and Negative Symptoms: Results From a Randomized Controlled Trial.
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Academic Article
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Lower On-Treatment Low-Density Lipoprotein Cholesterol and Major Adverse Cardiovascular Events in Women and Men: Pooled Analysis of 10 ODYSSEY Phase 3 Alirocumab Trials.
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Academic Article
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Efficacy and Safety of MIN-101: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial of a New Drug in Development for the Treatment of Negative Symptoms in Schizophrenia.
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Academic Article
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The effect of minocycline on symptoms in schizophrenia: Results from a randomized controlled trial.
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Academic Article
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Effect of cilostazol on walking distances in patients with intermittent claudication caused by peripheral vascular disease.
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Academic Article
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Effect of Adjunctive Estradiol on Schizophrenia Among Women of Childbearing Age: A Randomized Clinical Trial.
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Academic Article
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The brief negative symptom scale (BNSS): Sensitivity to treatment effects.
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Academic Article
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Effect of High-Dose Omega-3 Fatty Acids vs Corn Oil on Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk: The STRENGTH Randomized Clinical Trial.
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Academic Article
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Ziltivekimab for Treatment of Anemia of Inflammation in Patients on Hemodialysis: Results from a Phase 1/2 Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial.
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Academic Article
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Adjunctive Aspirin vs Placebo in Patients With Schizophrenia: Results of Two Randomized Controlled Trials.
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Academic Article
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Lipid lowering effects of the CETP inhibitor obicetrapib in combination with high-intensity statins: a randomized phase 2 trial.
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Academic Article
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Obicetrapib plus ezetimibe as an adjunct to high-intensity statin therapy: A randomized phase 2 trial.
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